Synthesis of an enantiomeric DNA oligomer and its T-HgII-T base-pair formation
نویسندگان
چکیده
منابع مشابه
Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury
Developing applications for metal-mediated base pairs (metallo-base-pair) has recently become a high-priority area in nucleic acid research, and physicochemical analyses are important for designing and fine-tuning molecular devices using metallo-base-pairs. In this study, we characterized the Hg(II)-mediated T-T (T-Hg(II)-T) base pair by Raman spectroscopy, which revealed the unique physical an...
متن کاملThe structure of metallo-DNA with consecutive thymine–HgII–thymine base pairs explains positive entropy for the metallo base pair formation
We have determined the three-dimensional (3D) structure of DNA duplex that includes tandem Hg(II)-mediated T-T base pairs (thymine-Hg(II)-thymine, T-Hg(II)-T) with NMR spectroscopy in solution. This is the first 3D structure of metallo-DNA (covalently metallated DNA) composed exclusively of 'NATURAL' bases. The T-Hg(II)-T base pairs whose chemical structure was determined with the (15)N NMR spe...
متن کاملAT base pair anions versus (9-methyl-A)(1-methyl-T) base pair anions.
The anionic base pairs of adenine and thymine, (AT)(-), and 9-methyladenine and 1-methylthymine, (MAMT)(-), have been investigated both theoretically and experimentally in a complementary, synergistic study. Calculations on (AT)(-) found that it had undergone a barrier-free proton transfer (BFPT) similar to that seen in other dimer anion systems and that its structural configuration was neither...
متن کاملTHE CATEGORY OF T-CONVERGENCE SPACES AND ITS CARTESIAN-CLOSEDNESS
In this paper, we define a kind of lattice-valued convergence spaces based on the notion of $top$-filters, namely $top$-convergence spaces, and show the category of $top$-convergence spaces is Cartesian-closed. Further, in the lattice valued context of a complete $MV$-algebra, a close relation between the category of$top$-convergence spaces and that of strong $L$-topological spaces is establish...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Symposium Series
سال: 2007
ISSN: 0261-3166,1746-8272
DOI: 10.1093/nass/nrm094